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Prion Biology and Diseases,2nd ed.

ISBN-10:0-87969693-1
ISBN-13:978-0-87969693-1

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General descriptionThis volume is a new edition of the most authoritative book on Prion Biology, first published in 1999 and edited by the Nobel Prize–winning founder of the field. This expanded edition has been completely updated, and includes chapters on therapeutics, and diagnostic methods and approaches This book is by far the most authoritative summary of the complex data that form the basis of our understanding of the molecular basis of this esoteric group of diseases.

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publication infoS. Prusiner, ed., Cold Spring Harbor Laboratory Press, 2004, 1050 pp., hard cover

Table Of Contents

Table of ContentsPRION BIOLOGY
Chapter 1: An Introduction to Prion Biology and Diseases
Chapter 2: Development of the Prion Concept
Chapter 3: Bioassays of Prions
Chapter 4: Transmission and Replication of Prions
Chapter 5: Structural Studies of Prion Proteins
Chapter 6: Doppel, a New PrP–like Mammalian Protein
FUNGAL PRIONS
Chapter 7: Prions of Yeast and Filamentous Fungi: [URE3], [PSI+], [PIN+], and [Het–s]
TRANSGENETICS AND CELL BIOLOGY OF PRIONS
Chapter 8: Knockouts, Knockins, Transgenics, and Transplants in Prion Research
Chapter 9: Transgenetic Investigations of the Species Barrier and Prion Strains
Chapter 10: Cell Biology of Prions
PRION DISEASES IN ANIMALS
Chapter 11: Scrapie, Chronic Wasting Disease, and Transmissible Mink Encephalopathy
Chapter 12: Bovine Spongiform Encephalopathy and Related Diseases
HUMAN PRION DISEASES
Chapter 13: Infectious and Sporadic Prion Diseases
Chapter 14: Inherited Prion Diseases
Chapter 15: Neuropathology of Prion Diseases
METHODOLOGY, BIOSAFETY, AND THERAPEUTICS
Chapter 16: Some Strategies and Methods for the Study of Prions
Chapter 17: Biosafety Issues in Prion Diseases
Chapter 18: Therapeutic Approaches to Prion Diseases
Glossary
Appendix
Index